Articles Posted in Diabetes

Collinslab-150x150Mukamal-144x150The National Institutes of Health, perhaps the world’s leading medical research institution, has moved fast to try to fix self-inflicted damage to its reputation caused by a controversial $100-million study on alcohol and its harms.

NIH Director Francis Collins halted the study, and an advisory group backed his action, lambasting researchers for soliciting funding and counsel from the alcohol industry for a work that purported to answer key and fundamental questions about booze but from its outset leaned toward seeing benefit in moderate drinking.

The New York Times deserves credit for digging into the dubious  actions by researchers supported by the National Institute on Alcohol Abuse and Alcoholism, an arm of NIH.

kidtv-300x225If Americans want to battle obesity, including among youngsters, one place to start is avoiding unhealthy food products hawked relentlessly by major league sports advertisers.

Weight woes plague grownups and show no signs of letting up — they’re increasing, instead, with 40 percent of Americans found to be obese in 2015 and 2016, a sharp increase over a decade earlier. The picture’s no prettier for young people, with the latest federal data showing the percentage of children ages 2 to 19 who are obese increased from 14 percent in 1999 to 18.5 percent in 2015 and 2016.

With studies showing that junk food and empty calories contribute significantly to making the nation an excessive waist-land, Vox, an online information site, deserves credit for pointing out how pervasive, insidious, and even accepted it has become for sports fans — especially young enthusiasts — to be barraged by advertising for fast and unhealthful meals, sugar-laden drinks and cereals, and foods full of fats, empty calories, and excess salt.

acp-A1C-300x184What are patients supposed to do when medical experts feud over key disease metrics like the optimal blood sugar level  for diabetics?

Here we go again, figuring out medical figures:  That’s because the American College of Physicians and the American Diabetes Association are tussling over the much-watched blood sugar test — the hemoglobin A1c. It’s also known just as the A1C or the HbA1c, or glycohemoglobin test.

As the Mayo Clinic describes the A1C, it “reflects your average blood sugar level for the past two to three months. Specifically, the A1C test measures what percentage of your hemoglobin — a protein in red blood cells that carries oxygen — is coated with sugar (glycated). The higher your A1C level, the poorer your blood sugar control and the higher your risk of diabetes complications.”

epipen-300x119Big Pharma’s rapacious profit-seeking can seem to hit no bounds, even if it afflicts millions: Just consider what federal and state regulators are mulling about the makers of a popular anti-allergy therapy and those who supply a critical diabetes medication.

The federal Food and Drug Administration has replied to Bloomberg News Service that, so far, in 2017, it has recorded 228 reports of EpiPen or EpiPen Jr. failures, and the failure of EpiPens to deploy correctly has been cited in seven deaths through mid-September.

The agency said it is monitoring closely these “adverse event complaints.” These are unconfirmed reports that do not necessarily tie a product to a harm. But they might constitute sufficient grounds to investigate further and to potentially order product recalls, though, so far, the FDA says it believes patients can keep using EpiPens on the market without worry.

cdccancer-271x300Those carrying around a few pounds extra, or maybe even a lot more, may want to get moving and to drop that excess weight for yet more compelling health causes: That’s because more than 630,000 Americans were diagnosed in 2014 with cancers linked to obesity or overweight, the federal Centers for Disease Control and Prevention has reported.

The CDC says 40 percent of all diagnosed cancers were associated with obesity. At a time when the nation is seeing some success in reducing overall rates of diagnosed cancers, a baker’s dozen of overweight-related cancers increased 7 percent between 2005 and 2014. Two out of three of the cancers occurred in those 50- to 74-years-old.

Federal officials have found that more than half of Americans don’t know there’s a connection between 13 kinds of cancers (see diagram) and excess weight. It took public health officials decades to persuade the public that smoking posed cancer health risks and people needed to stop—and Big Tobacco still resorts to unceasing, deceptive tactics to undermine this awareness.

booze-256x1024It’s more than happy hour chardonnays with office mates or malt liquors  at a summer barbecue.

Public health experts are warning that alcohol drinking is rising sharply, and in especially worrisome fashion for women, seniors, African Americans, Latinos, and Americans of Asian descent. As the nation struggles with addiction crises—especially a plague of opioid drug abuse—booze woes may be getting less than their deserved attention.

Our heavy and increasing alcohol consumption, as captured in a sizable and regular survey of Americans’ tippling habits, should be of big concern. That’s because experts note that it can “portend increases in many chronic co-morbidities in which alcohol use has a substantial role.”

obesity-300x161Although weight issues plague Americans as gravely as anywhere on the planet, obesity also has become a global woe, increasing sharply over the last three decades in 195 countries and afflicting an estimated 604 million adults and 108 million children—roughly 10 percent of the world’s population.

No nation on earth, even with the terrible toll that obesity takes in economic and health terms, has found a way to get its people skinnier and healthier: Weight woes are blowing up in disparate places like Saudi Arabia, Algeria, Egypt, Burkina Faso, Mali, and Guinea-Bissau, international researchers have reported in the New England Journal of Medicine. Obesity is now a major concern, too, for the people of China, Turkey, Venezuela, and Bhutan.

Public health experts worry about the skyrocketing numbers of overweight people around the planet because evidence shows obesity to be a major factor in heart disease, diabetes, cancer, and other debilitating conditions.  These afflictions, combined with weight issues—including among those considered to be too heavy but not necessarily obese—contributed to four million deaths in 2015 alone, said the experts, participating as part of the Global Burden of Disease initiative.

Blausen_0601_LaparoscopicGastricBanding-300x300They once got a ton of hype with radio, TV, and print ads, as well as billboard campaigns by proponents who later proved to be nothing less than sketchy. But the much-touted lap-band weight surgeries have fallen out of favor. The number of the procedures performed annually has nose-dived.

Researchers, based on a longer view, are finding that, among bariatric weight-loss options, lap-band surgeries offer some of the poorest results and result in frequent added procedures—at big costs, both economic and to disappointed, suffering patients.

Vox, the online news site, deserves credit for pulling together a painful review of what once was the most common way for overweight Americans, mostly women, to tackle one of the nation’s epidemic conditions: obesity.

Polycythemia vera is so rare that just under 3 or so per 100,000 American men, most older than 60, are diagnosed each year with this rare form of blood cancer. Pseudobulbar affect, or PBA, is an uncommon neurological condition afflicting as few as 2 million Americans, causing them to experience uncontrolled, inappropriate bouts of laughter or tears.

What  links these two unusual maladies? Big Pharma hype: Both have taken starring roles in audacious and apparently successful advertising and marketing campaigns that have surprised even experts in the field.

10650-insulin-diabetes-300x169Just under a century ago, a team of Canadian scientists made the breakthrough that led to widely available insulin as an effective treatment for diabetes, which then was a deadly disease. The researchers, who won the Nobel Prize, also made a jaw-dropping gesture to ensure their discovery would benefit the afflicted: They handed over their lucrative patent on insulin to the University of Toronto to ensure the fearsome illness would be conquered.

The university, alas, turned quickly to commercial drug makers, licensing them to produce the life-saving medication. And flash forward to now, and, after years of rising anger, a group of diabetes patients has sued three drug makers, asserting they systematically and fraudulently price-gouged them for their must-have treatment.

Insulin has become a $24 billion global market, with myriad profit-grabbing hands of distributors and supposed cost-controllers moving it from makers to patients, each middleman taking his piece. Patients say they’re aggravated that the various Big Pharma players appear to work in concert to send insulin’s price, in lockstep, skyrocketing. One vendor’s product carried a sticker price of $21 per vial two decades ago. It now costs $255 for the same amount.

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